Fibrates: Gemfibrozil should not be combined with statin therapy because of serious potential drug interaction

Channel
مذاكرة باطنة عامة Internal medicine study
@internalmedicinestudy
On this record: Topic · Growth · Engagement · Posts · Citations · Cite this entry
300subscribers
+241 since we began measuring on 11 August 2026
Risers and fallers across the register · movement among entries of Under 1,000.
Register entry
| Telegram ID | -1004332226722 |
|---|---|
| Type | Channel |
| Username | @internalmedicinestudy |
| Created | Between 1 June 2026 and 10 August 2026 — estimated from Telegram’s id allocation, not measured. How this range is calculated. |
| First recorded | 11 August 2026 |
| Last confirmed live | 16 September 2026 |
| Measurements held | 7 |
| Confirmed unchanged | 1 time, most recently 16 September 2026 |
| On Telegram | t.me/internalmedicinestudy |
Topic
Education — a classification, not a measurement. An on-box language model (Qwen3.6-35B-A3B-FP8, prompt version 1) read this channel’s own recent posts on 22 September 2026 and assigned it the closest of 31 fixed categories, at 99% confidence. This is a model’s judgement about what the channel is likely to be about, not a fact this register measured the way a subscriber count or a view count is measured — it can be revised on a later pass, and it carries no weight anywhere else on this page. How this classification works, and why it has no browse page of its own yet.
Growth
| Measured (UTC) | Subscribers | Change |
|---|---|---|
| 16 Sept 2026, 16:57 | 300 | +6 |
| 9 Sept 2026, 10:56 | 294 | +26 |
| 31 Aug 2026, 20:36 | 268 | +37 |
| 25 Aug 2026, 01:48 | 231 | +81 |
| 18 Aug 2026, 02:23 | 150 | +91 |
| 12 Aug 2026, 00:06 | 59 | no change |
| 11 Aug 2026, 20:30 | 59 | first reading |
Engagement
20 posts held, back to 10 August 2026 — the reader has not yet reached the start of this channel’s public history, so older posts may sit further back, unread. Read across 1 page of Telegram’s post history, 20 posts per page.
Nothing published in the last 30 days. ERR and ER are rolling 30-day measures, so there is nothing to compute — we hold 20 posts for this entry, the most recent from 11 August 2026. An engagement rate over an empty window would be a number about nothing.
Recent posts
وهنا بيتشغل على ال binding to matching messenger RNA (mRNA) يعني شق جيني .. بحيث إنه يمنع الترجمة translation بتاع الأر إن إيه وبالتالي يتم تكسيره ... كله على ال RNA بتاع بروتين ال PCSK9
Expected LDL-C reduction: 48%–52%‡
PCSK9 inhibitor: small interfering RNA »»» Utilizes endogenous RNA interference mechanism and directs catalytic breakdown of mRNA for PCSK9 and decreases degradation of the LDL receptor
فيه منها نوع تاني عبارة عن small interfering RNA زي ال Inclisiran
Bempedoic acid: Expected LDL-C reduction: monotherapy in patients with statin-attributed side effects, 21%–24% . combination with a statin, 17%–18%‡
ATP citrate lyase (ACLY) is a cytosolic enzyme that converts citrate and coenzyme A into acetyl-CoA and oxaloacetate using ATP. It links sugar metabolism to fat and cholesterol production, and supplies acetyl groups for protein and histone modification.
الجملة دي هتلاقيها في وظيفة كذا دواء: الاستاتين وال Ezetimibe وال Bempedoid acid: increases LDL receptor expression on the surface of hepatocytes
عندنا نوع تاني من الأدوية زي ال Bempedoic acid ودا تبع ATP citrate lyase inhibitor ال ATP citrate lyase عبارة عن إنزيم موجود في الكبد وأساسي في تصنيع الكوليسترول والدهون ومهم في عملية تحويل السكريات إلى دهون وكوليسترول .. يعني إنزيم أساسي في سلسلة التصنيع ... وال Bempedoic acid بيقفل شغله وبالتالي بيقفل تصنيع الكوليسترول ... وكمان بيزود عدد مستقبلات ال LDL
Ezetimibe: Blocks the sterol transporter protein, NPC1L1, to inhibit intestinal and biliary sterol absorption; increases LDL receptor expression on the surface of hepatocytes secondary to reduced hepatic sterol levels
ال Ezetimibe بيتشغل على تقليل امتصاص الكوليسترول (Sterol) وكمان بيزود مستقبلات ال LDL
PCSK9 inh. action: binds to PCSK9 in the circulation and decreases degradation of LDL receptors
Showing the 12 most recent of 20 posts we hold for @internalmedicinestudy. View and reaction counts are the latest single reading for each post, not a live figure, and a recent post is still accumulating both. A view count marked ≈ was rounded by Telegram before we ever saw it — t.me prints views in full below 1,000 and to three significant figures above, so ≈1,200,000 means somewhere between 1,150,000 and 1,249,999. Unmarked counts are exact. Text is reproduced from the public post preview and truncated for length.
Forward network
Republished by
Channels on the register that have forwarded this channel's posts into their own feed.
Built only from forwarded posts we have actually read, on both sides. Coverage is early and deliberately incomplete: a missing link means we have not read the post that would prove it, never that the relationship does not exist. Counts are distinct forwarded posts observed, so they only ever go up as we read more.
Mentions
Named by 1 registered channel — every channel on the register whose own posts have named this one, by its current username or any other username it currently holds, merged from two separately captured readings of the same fact so a namer caught by only one of them is not missed and a namer both caught is not counted twice. A username this channel has since dropped is not matched — that handle may belong to someone else now, and crediting today’s namer to yesterday’s owner would misattribute it.
Named by
Channels on the register whose posts name this channel's handle.
A mention is a weaker signal than a forward and is counted separately for that reason — naming a channel is not republishing it, and a handle in a post body is easy to place deliberately. The post counts beside each row below are distinct posts in which the handle appeared, from posts we have read on both sides — the “Named by N registered channels” figure above is a different count, of distinct NAMING CHANNELS rather than posts, and is not the sum of the rows under it.
Cite this entry
A live page changes as we take new readings, so a citation should name the measurement it is based on, not just the URL. The line below cites the subscriber count as measured 16 September 2026 — this entry's latest reading, not the date you are reading this.
“مذاكرة باطنة عامة Internal medicine study” (@internalmedicinestudy), 300 subscribers as measured 16 September 2026. Telegram Register, tgregister.com/channel/internalmedicinestudy.
Full measurement history, CC BY 4.0. Every reading this register holds for this entry, not just the latest one, as a dated, downloadable record: CSV · JSON. Free to use with attribution to tgregister.com. Each file carries its own generation timestamp, which is the figure to cite for exactly when the data was retrieved.