20 Nov 2024, 01:30 UTC531 views2 reactionsread 8 August 2026 Designer cells 'reboot' immune system in 3 different autoimmune diseases
In an early-stage clinical trial, scientists explored the potential of designer immune cells to "reboot" the immune systems of patients with autoimmune diseases using a form of CAR T cell therapy, traditionally used for blood cancers like leukemia. This innovative approach involved a single infusion of genetically modified T cells to eliminate r…
👍2
20 Nov 2024, 01:30 UTC481 views1 reactionsread 8 August 2026 How human brains got so big: cells learned to handle stress that comes with size
In this intriguing exploration of human brain evolution, researchers have uncovered how our disproportionately large brains manage the stress associated with their size. By studying dopamine-producing neurons in humans and comparing them with those in other primates, scientists found that human neurons express more genes that enhance ant…
❤1
20 Nov 2024, 01:29 UTC358 viewsread 8 August 2026 Enormous cache of rare earth elements hidden inside coal ash waste
Recent research from The University of Texas at Austin reveals that coal ash, a byproduct of burned coal, contains significant quantities of rare earth elements (REEs), potentially bolstering the U.S. supply without new mining. This "trash to treasure" approach could reduce environmental impacts while addressing the U.S.'s reliance on REE imports, pri…
20 Nov 2024, 01:28 UTC295 viewsread 8 August 2026 Why Smart C Coders Love Lua
Embedded systems have traditionally relied on C and C++ for their performance and control. However, with the rise of IoT and edge devices, developers are increasingly turning to Lua, especially when paired with frameworks like Xedge. Lua offers a higher-level approach, simplifying development and reducing time-to-market. Unlike C, Lua is garbage-collected, easing memory management and mini…
20 Nov 2024, 01:27 UTC222 viewsread 8 August 2026 PaCMAP: Large-Scale Dimension Reduction with Both Global and Local Structure [pdf](https://news.ycombinator.com/item?id=42189253)
In this paper, we explore the intricacies of dimension reduction (DR) techniques like t-SNE, UMAP, and TriMap, which are pivotal for data visualization. These methods often face a trade-off between preserving global and local structures. Our research aims to understand the critical aspects…
20 Nov 2024, 01:25 UTC187 viewsread 8 August 2026 Joining the Shopify Board of Directors
In joining Shopify's Board of Directors, I am thrilled to engage with the monumental scale and impact of Shopify's operations. Tobi has built a remarkable technical organization, employing a third of the Rails Core Team and contributing significantly to the Ruby on Rails community. My decision to join was not only driven by gratitude but also by a desire to tackle programming ch…
20 Nov 2024, 01:25 UTC163 viewsread 8 August 2026 Elasticsearch Was Great, but Vector Databases Are the Future
The article from The New Stack argues that while Elasticsearch has been a staple for keyword-based search, the future lies in vector databases, which excel in semantic search. As AI advances, semantic search, which understands the meaning behind queries, is becoming crucial. Vector databases, like Milvus, offer a hybrid approach by combining semantic and ke…
20 Nov 2024, 01:24 UTC141 viewsread 8 August 2026 Ask HN: Bluesky Accounts Worth Following for HN Enthusiasts
Hey fellow HN enthusiasts! I'm on the hunt for Bluesky accounts that echo the tech-centric discussions we cherish on Hacker News. If you know of any profiles that consistently share intriguing and insightful tech content, I'd love your recommendations. Let's curate a feed that keeps us informed and inspired, much like our beloved HN community.
20 Nov 2024, 00:54 UTC126 viewsread 8 August 2026 Microsoft built a PC that can't run local apps – Windows 365 Link starts at $349
Microsoft has unveiled the Windows 365 Link, a mini-PC designed to operate Windows 365 Cloud PCs, starting at $349. Aimed at businesses, this device requires a separate Windows 365 subscription, costing between $28 to $315 monthly per user. The most popular option, at $66 per month, totals nearly $2,000 over two years, including hardware…
20 Nov 2024, 00:50 UTC121 viewsread 8 August 2026 Reexamination of 1975 "Edmund Fitzgerald" Storm Using Today's Technology [pdf](https://news.ycombinator.com/item?id=42102308)
In "Reexamination of the 1975 'Edmund Fitzgerald' Storm Using Today's Technology," authors Thomas R. Hultquist, Michael R. Dutter, and David J. Schwab revisit the infamous storm that led to the sinking of the Edmund Fitzgerald on Lake Superior. Utilizing modern numerical weather prediction mod…
19 Nov 2024, 23:50 UTC104 viewsread 8 August 2026 We assume damage to Baltic Sea cables was sabotage, German Defence minister
Germany has expressed concerns over potential sabotage after two undersea fiber-optic cables in the Baltic Sea were damaged. The cables, linking Finland to Germany and Sweden to Lithuania, were severed, prompting suspicions of a deliberate attack. German Defence Minister Boris Pistorius stated that accidental damage is unlikely, suggesting sa…
19 Nov 2024, 23:50 UTC90 viewsread 8 August 2026 Important information to all residents of Sweden – In case of crisis or war [pdf](https://news.ycombinator.com/item?id=42188855)
This brochure, distributed to every Swedish household by the Swedish Civil Contingencies Agency (MSB), provides crucial guidance on preparing for crises or war. It emphasizes the importance of unity and resilience in the face of threats like armed conflict, cyber attacks, and disinformation…
Showing the 12 most recent of 20 posts we hold for @hn_summary. View and reaction counts are the latest single reading for each post, not a live figure, and a recent post is still accumulating both. A view count marked ≈ was rounded by Telegram before we ever saw it — t.me prints views in full below 1,000 and to three significant figures above, so ≈1,200,000 means somewhere between 1,150,000 and 1,249,999. Unmarked counts are exact. Text is reproduced from the public post preview and truncated for length.